Diabetes : Japan AOIs

Diabetes : Japan AOIs

 

 
 

The following areas are of interest to the Investigator Studies Program Committee:

  • Effects of DPP-4i and SGLT2i combination in sub-populations
    (e.g., elderly, obesity, NASH, NAFLD, insulin or on prior GLP-1RA therapy).

  • Impact of DPP-4i and SGLT2i combination on glucose fluctuation.

  • Effects of DPP-4i and SGLT-2i combination beyond glucose metabolism
    (macrovascular complications, heart failure, and other diabetic complications).

  • Clinical and mechanistic studies on the effects of DPP-4i and SGLT2i combination on alpha- and beta-cell functions.

  • Impact of fixed dose combination on treatment burden, adherence, satisfaction, and patient preference.